Wednesday, November 27, 2019

How to Overcome Teenagers Problem Essay Example

How to Overcome Teenagers Problem Essay Example How to Overcome Teenagers Problem Essay How to Overcome Teenagers Problem Essay Random acts of kindness are a means by which we make a deliberate attempt to brighten another persons day by doing something thoughtful, nice, and caring for them. Kindness is a way of showing others that they count and that even in the face of hostility and selfishness, youre making a stand for kindness.Originally associated with Anne Herbert, who is said to have once written Practice random acts of kindness and senseless acts of beauty on a place mat in a restaurant,this concept has become an organized celebration through various events around the world, as well as referring to a general call to action in the name of kindness. And you dont need to wait for someone else to instigate a day or week of celebrations to practice random acts of kindness; you can put them into play any time you like!By doing kind acts for others, youre helping to create kindness-aware communities that value generosity of spirit and action and kindness toward others as essential parts of a healthy community . Here are some suggestions for encouraging others with your random acts of kindness. EXAMPLES OF ACTS OF RANDOM KINDNESS!!!!! Be kind. Kindness as an attitude is infectious. When youre willing to share your kindness, others will be inspired by your example and think about doing something as kind themselves.Fan that flame by being kind to everyone. Be thoughtful. Random acts of kindness can be shown through thoughtfulness about the needs of others. Use your manners as a form of kindness. Manners arent dead, theyve just been forgotten in many ways. Yet, manners are the bedrock of courteous and kind relations and their use is an indication of respect for others. Hold doors open for others, hold an umbrella over someone in the rain, and be on time for everyone youve promised to meet. Give out compliments generously.Theres usually an awkward silence when youre stuck in an elevator or waiting in a queue with a stranger. Instead of staring at the floor, find something you like about the o ther person and compliment him/her on it. Not only will it make him/her feel good, it just might kick off a conversation with a new friend. Volunteer. Offer helping hands. Do you ever see homeless people and feel overwhelmed by your inability to make a difference? Even if you cant save them all, you can do a lot with one small act.Buy a pair of gloves or dig up an old blanket, and give them to someone whos living in the cold streets or to any organization that serves the homeless. Share a little wealth around. Forgive somebody. You be amazed at the ripple effect an ounce of forgiveness can have in your life and in the lives of others. Unburden yourself of the past and think kind thoughts again about that person. Share a smile. When meeting a new person, or even chatting with an old one, express joy. Show that youre happy to be with them, and that they make you happy

Saturday, November 23, 2019

Biography of Ferdinand Marcos, Philippines Dictator

Biography of Ferdinand Marcos, Philippines' Dictator Ferdinand Marcos (September 11, 1917–September 28, 1989) ruled the Philippines with an iron fist from 1966 to 1986. Critics charged Marcos and his regime with crimes like corruption and nepotism. Marcos himself is said to have exaggerated his role in World War II. He also murdered a family political rival. Marcos created an elaborate cult of personality. When that state-mandated adulation proved insufficient for him to maintain control, President Marcos declared martial law. Fast Facts: Ferdinand Marcos Known For: Philippines dictatorAlso Known As: Ferdinand Emmanuel Edralin Marcos Sr.Born: September 11, 1917  in Sarrat, PhilippinesParents: Mariano Marcos,  Josefa EdralinDied: September 28, 1989  in Honolulu, HawaiiEducation: University of the Philippines, College of LawAwards and Honors: Distinguished Service Cross, Medal of HonorSpouse: Imelda Marcos  (m. 1954–1989)Children: Imee,  Bongbong,  Irene, Aimee (adopted)Notable Quote: I often wonder what I will be remembered in history for. Scholar? Military hero? Builder? Early Life Ferdinand Edralin Marcos was born on Sept. 11, 1917, to Mariano and Josefa Marcos in the village of Sarrat, on the island of Luzon, the Philippines. Persistent rumors say that Ferdinands biological father was a man named Ferdinand Chua, who served as his godfather. Officially, however, Josefas husband Mariano Marcos was the childs father. Young Ferdinand Marcos grew up in a privileged milieu. He excelled at school and took an eager interest in things like boxing and shooting. Education Marcos attended school in Manila. His godfather Ferdinand Chua may have helped pay for his educational expenses. During the 1930s, the young man studied law at the University of the Philippines, outside of Manila. This legal training would come in handy when Marcos was arrested and tried for a 1935 political murder. In fact, he continued his studies while in prison and even passed the bar exam with flying colors from his cell. Meanwhile, Mariano Marcos ran for a seat on the National Assembly in 1935 but was defeated for a second time by Julio Nalundasan. Assassinates Nalundasan On Sept. 20, 1935, as he was celebrating his victory over Marcos, Nalundasan was shot dead at his home. Ferdinand, then 18, had used his shooting skills to kill Nalundasan with a .22-caliber rifle. Marcos was indicted for the killing and convicted by a district court in November of 1939. He appealed to the Supreme Court of the Philippines in 1940. Representing himself, Marcos managed to get his conviction overturned despite strong evidence of his guilt. Mariano Marcos and (by now) Judge Chua may have used their political power to influence the outcome of the case. World War II At the outbreak of World War II, Marcos was practicing law in Manila. He soon joined the Filipino Army and fought against the Japanese invasion as a combat intelligence officer in the 21st Infantry Division. Marcos saw action in the three-month-long Battle of Bataan, in which the Allied forces lost Luzon to the Japanese. He survived the Bataan Death March, a week-long ordeal that killed about a quarter of Japans American and Filipino POWs on Luzon. Marcos escaped the prison camp and joined the resistance. He later claimed to have been a guerrilla leader, but that claim has been disputed. Post-War Era Detractors say that Marcos spent the early post-war period filing false compensation claims for wartime damages with the United States government, such as a claim for almost $600,000 for 2,000 imaginary cattle of Mariano Marcos. Marcos also served as a special assistant to the first president of the newly independent Republic of the Philippines, Manuel Roxas, from 1946 to 1947. Marcos served in the Philippines House of Representatives from 1949 to 1959 and the Senate from 1963 to 1965 as a member of Roxas Liberal Party. Rise to Power In 1965, Marcos hoped to secure the Liberal Party nomination for the presidency. The sitting president, Diosdado Macapagal (father of current president Gloria Macapagal-Arroyo), had promised to step aside, but he reneged and ran again. Marcos resigned from the Liberal Party and joined the Nationalists. He won the election and was sworn in on December 30, 1965. President Marcos promised economic development, improved infrastructure, and good government to the people of the Philippines. He also pledged help to South Vietnam and the U.S. in the Vietnam War, sending more than 10,000 Filipino soldiers to fight. Cult of Personality Ferdinand Marcos was the first president to be reelected to a second term in the Philippines. Whether his reelection was rigged is a subject of debate. In any case, he consolidated his hold on power by developing a cult of personality, like those of Joseph Stalin or Mao Zedong. Marcos required every business and classroom in the country to display his official presidential portrait. He also posted giant billboards bearing propagandistic messages across the country. A handsome man, Marcos had married former beauty queen Imelda Romualdez in 1954. Her glamour added to his popularity. Martial Law Within weeks of his reelection, Marcos faced violent public protests against his rule by students and other citizens. Students demanded educational reforms; they even commandeered a fire truck and crashed it into the Presidential Palace in 1970. The Filipino Communist Party reemerged as a threat. Meanwhile, a Muslim separatist movement in the south urged succession. President Marcos responded to all of these threats by declaring martial law on September 21, 1972. He suspended habeas corpus, imposed a curfew, and jailed opponents like Benigno Ninoy Aquino. This period of martial law lasted until January 1981. Dictatorship Under martial law, Marcos took extraordinary powers for himself. He used the countrys military as a weapon against his political enemies, displaying a typically ruthless approach to opposition. Marcos also awarded a huge number of government posts to his and Imeldas relatives. Imelda herself was a member of Parliament (1978-84); Governor of Manila (1976-86); and Minister of Human Settlements (1978-86). Marcos called parliamentary elections on April 7, 1978. None of the members of jailed former Senator Benigno Aquinos LABAN party won their races. Election monitors cited widespread vote-buying by Marcos loyalists. In preparation for Pope John Paul IIs visit, Marcos lifted martial law on Jan. 17, 1981. Nonetheless, Marcos pushed through legislative and Constitutional reforms to ensure that he would retain all of his extended powers. It was purely a cosmetic change. Presidential Election of 1981 For the first time in 12 years, the Philippines held a presidential election on June 16, 1981. Marcos ran against two opponents: Alejo Santos of the Nacionalista Party and Bartolome Cabangbang of the Federal Party. LABAN and Unido both boycotted the election. Marcos received 88% of the vote. He took the opportunity in his inauguration ceremony to note that he would like the job of Eternal President. Death of Aquino Opposition leader Benigno Aquino was released in 1980 after spending nearly eight years in prison. He went into exile in the United States. In August 1983, Aquino returned to the Philippines. Upon arrival, he was hustled off the plane and shot dead on the runway at the Manila Airport by a man in a military uniform. The government claimed that Rolando Galman was the assassin; Galman was immediately killed by airport security. Marcos was ill at the time, recovering from a kidney transplant. Imelda may have ordered Aquinos killing, which sparked massive protests. Later Years and Death Aug. 13, 1985, was the beginning of the end for Marcos. Fifty-six members of Parliament called for his impeachment for graft, corruption, and other high crimes. Marcos called a new election for 1986. His opponent was Corazon Aquino, the widow of Benigno. Marcos claimed a 1.6 million vote victory, but observers found an 800,000-vote win by Aquino. A People Power movement quickly developed, driving the Marcoses into exile in Hawaii, and affirming Aquinos election. The Marcoses had embezzled billions of dollars from the Philippines. Imelda famously left more than 2,500 pairs of shoes in her closet when she fled Manila. Marcos died of multiple organ failure in Honolulu on Sept. 28, 1989. Legacy Marcos left behind a reputation as one of the most corrupt and ruthless leaders in modern Asia. The Marcoses had taken with them more than $28 million in cash in Philippine currency. President Corazon Aquinos administration said this was only a small part of the Marcoses illegally gained wealth. Marcos excesses are perhaps best exemplified by his wifes extensive shoe collection. Imelda Marcos is reported to have gone on shopping sprees using state money to buy jewelry and shoes. She amassed a collection of more than 1,000 pairs of luxury shoes, which earned her the nickname, Marie Antoinette, with shoes. Sources Britannica, The Editors of Encyclopaedia. â€Å"Ferdinand Marcos.†Ã‚  Encyclopà ¦dia Britannica, 8 Mar. 2019..Ferdinand E. Marcos Republic of the Philippines-Department of National Defense.â€Å"Ferdinand Marcos Biography.†Ã‚  Encyclopedia of World Biography.

Thursday, November 21, 2019

Shadow Side of Leadership Assignment Example | Topics and Well Written Essays - 750 words

Shadow Side of Leadership - Assignment Example Harper’s article explains the shadow side of leadership as being founded on â€Å"A combination of self-centered attitudes, motivations, and behaviors that have adverse effects on subordinates, the corporation, and the mission performance† (Harper 2014). Toxic leadership has numerous ethical concerns that violate both the code of ethics and conduct and code of human resources (Mason 1993). In every organization, a leader stands at the peak of the hierarchy or structure of management. Followers or employees stand at the base of the hierarchy. Therefore, employees report to the leaders. Toxic leaders lack respect, integrity, competence, and general responsibility towards the employees. The outcomes of such are high staff turnover, job dissatisfaction, employee disempowerment, and redundancy. According to Peters and Austin, (2003) leadership is not innate. Leaders must be followers at one point in time. It should be noted that, a leader decides on the best way possible to govern the organization through working with a human resources team. There are many ways to lead a team effectively. Mahatma Gandhi, Martin Luther King, and Steve Jobs portrayed effective leadership styles. In the same way, leaders can prevent themselves from being perceived as toxic and ensure that those reporting to them become the best that they can be. Leaders ought to integrate the code of ethics and conduct and code of human resources to govern a human resources team effectively. Both the code of ethics and conduct and code of human resources require that leaders uphold respect, integrity, competence, and general responsibility (Embse et al., 2010). In addition, effective leadership ought to focus on empowering the employees, who are prospective leaders. Leaders enhance job security among the empl oyees by ensuring that they [employees] realize their full potential. The leadership style adopted

Tuesday, November 19, 2019

The African American experience in colonial and antebellum North Term Paper

The African American experience in colonial and antebellum North America - Term Paper Example Food was scarce and even opted to eat corpses. Mostly, slaves came from Africa, the Caribbean and South America and by 1619; there were more than a million slaves in Virginia (Zinn 4). The whites and the Indians practiced their culture while the Africans were humiliated, and their culture was deemed to be inferior. Ironically, the African civilization was at par to that of Europe in terms of technology. Since slaves were treated harshly, they started rebellions that were crushed mercilessly. We are told that even some of the offenders were burnt alive and some hanged (Zinn 8). Later on, the black slaves and white servants started colluding to cause mayhem but those caught were equally punished. Racial discrimination is evident in this article because whites were considered superior to blacks hence given privileges like ownership of weapons and enough food. During this time, slaves also started demanding for their freedom (Zinn 12). The antebellum period was a time of slavery in North America whereby discriminatory laws were in place. Despite the existence of this laws, the African Americans were allowed to participate in societal duties. The black men were allowed to enlist themselves into the army that fought the 1812 American revolutionary war. In relation to these laws, Englishmen were not allowed to marry a Negro woman. However, if by chance an Englishman committed fornication with a Negro man or woman, he was fined (Bacon 42). On the other hand, non-Christians who were brought to the United States by land or sea and were not considered free (Bacon 42). IN this era, nobody was allowed to buy anything from a slave. Any woman who was a slave and conceived a child while serving her master was fined thousand pounds of tobacco. The child father was required to provide security to the church wardens of the parish where the child shall be taken care of and any complaints from the wardens reported to the

Sunday, November 17, 2019

Insulin-Dependent Diabetes Mellitus Essay Example for Free

Insulin-Dependent Diabetes Mellitus Essay Etiology of Diabetes Mellitus â€Å"Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels.† (Association, National Center for Biotechnology Information , 2009, p. 1) â€Å"The cause of type 1 and type 2 diabetes remains a mystery. Although genetic factors may play a role†. (Association, Diagnosis and Classification of Diabetes Mellitus, 2010, pp. 562-569) Diabetes mellitus generally results from an insulin deficiency or resistance. Insulin transports sugar into cells for use as energy and storage as glycogen which is a carbohydrate. Insulin also stimulates protein synthesis and free fatty acid storage. Insulin deficiency or resistance compromises the bodies access to essential nutrients for fuel and storage. Several processes called pathogens(capable of causing disease) are involved in the development of diabetes. The reasons of the abnormalities in carbohydrates, fats, and protein metabolism in diabetes is deficient action of insulin on certain tissues in the body. The term Deficient insulin action, results from not enough insulin secretion and/or diminished tissue response to insulin at one or more points in the complex pathways of hormone action (a chemical messenger that transports a signal from one cell to another). If insulin secretion is blocked or impaired, then defects in the insulin action occur in the same patient, and it is often unclear which abnormality, the cause of the hyperglycemia. (Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, 1997, pp. 107-109) Type 1 Diabetes Mellitus is defined as an autoimmune disorder or simply put an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body actually attacks its own cells (What-is-Autoimmune-Disease). This form of diabetes is brought on by a viral infection in which certain cells are destroyed which leads to absolute (complete) insulin deficiency and is usually diagnosed in childh ood. Many pediatric patients that have diabetes normally have Type 1 diabetes and therefore a lifetime dependency on insulin. â€Å"Diabetes mellitus (DM) is a chronic metabolic disorder caused by an absolute or relative deficiency of insulin, an anabolic hormone.† (Diabetes-MellitusDefinition-Causes-Symptoms-and-Treatment) In contrast Type 2 Diabetes Mellitus is a more progressive disorder in which the glandular organ in the digestive system and endocrine system known as the pancreas makes less insulin over time. Because the body’s cells have a reduced response to insulin, symptoms arise that include poor control of liver glucose (sugar) output, a decrease in cell function, and eventually cell failure. The true cause of Type 2 diabetes is unknown; however, it usually occurs in adulthood, from heredity, excessive obesity and sedentary lifestyle. These lifestyle choices may play a major role in its development. For both types of diabetes the main feature is chronic high blood glucose (sugar) levels (Ignatavicius, 2006). Risk factors for Diabetes Mellitus include obesity, physiologic or emotional stress, which can lead to an elevation of stress hormone levels. In women sometimes pregnancy, which causes weight gain and increases levels of estrogen and placental hormones, may aggravate insulin output. There is also something called the metabolic syndrome which is a combination of medical disorders that, when occurring together, increase the risk of developing cardiovascular disease and diabetes. There are also some medications that can provoke the effects of insulin, including thiazide diuretics, adrenal corticosteroids, and hormonal contraceptives (Mackay, 2004). Classification of Diabetes Mellitus There are several different types of diabetes mellitus; they may differ in cause, clinical course, and treatment. The major classifications of diabetes are: * Type 1 diabetes (insulin dependent diabetes mellitus) is caused by B-cell destruction, usually leading to absolute insulin deficiency a) Immune mediated b) Idiopathic * Type 2 diabetes (previously referred to as non-insulin dependent diabetes mellitus) ranges from those with predominant insulin resistance associated with relative insulin deficiency, to those with a predominantly insulin secretory defect with insulin resistance (Alberti, 2007). Insulin is secreted by beta cells, which are one of four types of cells in the islets of Langerhans (dendritic cells = antigen-presenting immune cells) in the pancreas. Insulin is an anabolic, or storage hormone. When a person eats a meal, insulin secretion increases and moves sugar from the blood into muscle, liver, and fat cells. In those cells, insulin transports and metabolizes glucose for energy. Later it stimulates storage of sugar in the liver and muscle (in the form of glycogen). Following this it signals the liver to stop the release of glucose, then enhances storage of dietary fat in adipose which is a storage tissue. Finally it accelerates the transport of amino acids (derived from dietary protein) into the body’s cells. â€Å"Insulin also inhibits the breakdown of stored glucose, protein, and fat. During fasting periods (between meals and overnight), the pancreas continuously releases a small amount of insulin (basal insulin); another pancreatic hormone called glucagon (secreted by the alpha cells of the islets of Langerhans) is released when blood glucose levels decrease and stimulate the liver to release stored glucose. The insulin and the glucagon together maintain a constant level of glucose in the blood by stimulating the release of glucose from the liver. Initially, the liver produces glucose through the breakdown of glycogen (glycogenolysis). Glycogen is the storage form for glucose in the liver and muscles. Glycogenolysis is the conversion of glycogen into glucose in the liver. After 8 to 12 hours without food, the liver forms glucose from the breakdown of non-carbohydrate substances, including amino acids (gluconeogenesis)† (Hamouda, 2012). Type 1 Diabetes Treatment and Study This form of diabetes is immune-mediated in over 90% of cases and idiopathic in less than 10%. The rate of pancreatic B cell destruction is quite variable, being rapid in some individuals and slow in others. Type 1 diabetes is usually associated with ketosis in its untreated state. It occurs at any age but most commonly arises in children and young adults with a peak incidence before school age and again at around puberty. It is a catabolic disorder in which circulating insulin is virtually absent, plasma glucagon is elevated, and the pancreatic B cells fail to respond to all insulinogenic stimuli. Exogenous insulin is therefore required to reverse the catabolic state, prevent ketosis, reduce the hyperglucagonemia, and reduce blood glucose. Clinical manifestations of all types of diabetes include the â€Å"three Ps†: polyuria, polydipsia, and polyphagia. Polyuria (increased urination) and polydipsia (increased thirst) occur as a result of the excess loss of fluid associated with osmotic diuresis. The patient also experiences polyphagia (increased appetite) resulting from the catabolic state induced by insulin deficiency and the breakdown of proteins and fats. Other symptoms include fatigue and weakness, sudden vision changes, tingling or numbness in hands or feet, dry skin, skin lesions or wounds that are slow to heal, and recurrent infections (Hamouda, 2012, p. para. 8). The onset of type 1 Diabetes may also be associated with sudden weight loss or nausea, vomiting, or abdominal pains. (Association, Diagnosis and Classification of Diabetes Mellitus, 2010) In recent years, there has been increasing interest in the impact of diabetes mellitus on the central nervous system (Lukovits TG, 1999).Clinically and epidemiologically, it has been shown that diabetes mellitus is an important risk factor for cerebrovascular accidents (Kannel WB, 1979), and may underlie many of the neuropsychological and cognitive deficits observed in diabetic patients (CM, 1988). Few studies have sought to establish the pathophysiological mechanisms that occur before these deficits appear, with a view to detecting early subclinical abnormalities that could serve as markers of the risk for stroke in patients who might benefit from preventive treatment. The study I read was performed in 15 insulin-dependent diabetics (eight men and seven women) with no history of central neurological symptoms. Their ages ranged from 27 to 59 years (mean 46 ±8 years) and the mean time since diagnosis of diabetes mellitus was 19 ±6 years. The characteristics of the patients are given in the Table below. The study was been reviewed by the hospitals ethics clinical committee, and before being enrolled each patient gave written informed consent. Characteristics of study subjects No. 15 Gender (M/F) 8/7 Age (years) 46 ±8 Arterial hypertension (yes/no) 5/12 Total cholesterol (mg/dl) 214 ±49 Time from diagnosis of IDDM (years) 19 ±6 Hemoglobin A1C (%) 8.19 ±0.8 Diabetic nephropathy (no/micro/macro albuminuria) 10/1/4 Diabetic retinopathy (yes/no) 7/8 Diabetic neuropathy (yes/no) 7/8 IDDM, Insulin-dependent diabetes mellitus The study dealt with the Cerebrovascular reserve (CVR) which is the capacity of cerebral arteries and arterioles to dilate, thus increasing blood flow in areas of decreased perfusion pressure (WJ, 1991). It is one of the first mechanisms of the brain to be activated in cases of hemodynamic compromise and is an early indicator of its existence (Baron JC, 1981). The chemical Acetazolamide, a carbonic anhydrase inhibitor, induces dilatation of the cerebral microvasculature and has been widely used in assessing CVR in large series of patients with different cerebrovascular disorders. (Julio F. Jimà ©nez-Bonilla, 2001). The study concluded that Insulin-dependent diabetic patients with no clinical history of neurological disorders present baseline abnormalities in cerebral perfusion and a decrease in CVR in extensive areas of the brain. The decrease in CVR and the behavior of baseline subclinical abnormalities after administration of acetazolamide suggested the existence of chronic cerebrovascular disease, the severity of which varied between patients and was better assessed with this technique than with baseline SPET (PET scan). In addition, the introduction of acetazolamide made it possible to classify baseline irregularities as being of probable metabolic origin or of probable ischemic origin. They concluded that the post-acetazolamide brain SPET is a valid tool which, in comparison with baseline SPET, provided additional information on cerebral perfusion in insulin-dependent diabetes. The technique should prove useful in evaluating future preventive strategies aimed at reducing the incidence of complications in diabetics. (Julio F. Jimà ©nez-Bonilla, 2001) The main goal of diabetes treatment is to normalize insulin activity and blood glucose levels to reduce the development of vascular and neuropathic complications. Insulin is indicated for type 1 diabetes as well as for type 2 diabetic patients with insulin openia whose hyperglycemia does not respond to diet therapy either alone or combined with other hypoglycemic drugs. The therapeutic goal for diabetes management is to achieve normal blood glucose levels (euglycemia) without hypoglycemia and without seriously disrupting the patient’s usual lifestyle and activity. There are five components of diabetes management †¢ Nutritional management – teaching the patient to eat properly and manage their diet accordingly. †¢ Exercise †¢ Monitoring – Use of a glucose meter and watching their numbers. †¢ Pharmacologic therapy – medicines that help level off sugars in their system. †¢ Education – finding out all the information they can about the disease so they will be informed as to the preventative measures taken to lead a more normal life. Bibliography Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. (1997). Diabetes Care, 20:1183-97. CITATIONS AND CLINICIANS NOTES: ETIOLOGY, PREDICTION, AND INCIDENCE OF DIABETES. (2005). Current Medical Literature: Diabetes, 22(2), 32-33. Alberti, K. M. (2007). International Diabetes Federation: a consensus on Type 2 diabetes prevention. Diabetic Medicine, 24(5), 451-463. doi:10.1111/j.1464-5491.2007.02157.x. Association, A. D. (2009, January). National Center for Biotechnology Information . Retrieved from PMC US National Library of Medicine : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613584/ Association, A. D. (2010, January). Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, pp. 562-569. Baron JC, B. M. (1981). Reversal of focal â€Å"misery-perfusion syndrome† by extra-intracranial arterial bypass in hemodynamic cerebral ischemia. A case study. Stroke, 12: 454-459. CM, R. (1988). Neurobehavioral complications of type I diabetes. Examination of possible risk factors. Diabetes Care, 11: 499-505. Diabetes-MellitusDefinition-Causes-Symptoms-and-Treatment. (n.d.). Retrieved 12 15, 2012, from www.healthguidance.org: http://www.healthguidance.org/entry/7366/1/Diabetes-MellitusDefinition-Causes-Symptoms-and-Treatment.html Hamouda, M. (2012, May 24).

Thursday, November 14, 2019

The Power of a Woman :: essays research papers fc

The Power of a Woman The familiar saying "Behind every great man is an even greater woman" can certainly hold true in many cases. A woman may very well be the driving force behind any successful man. However, a woman can also use her strong influence in a negative way. This can be seen in Macbeth, where Lady Macbeth is the evil force behind Macbeth's cruelty and evil doings. In Shakespeare's Macbeth, Lady Macbeth is the main reason that Macbeth is transformed from a noble, respected Thane into a ruthless, murderous character. Lady Macbeth fuels his inner desire for power and brings forth his greed and ambition, which both eventually lead to his downfall. The tactics that Lady Macbeth use to drive her husband to this downfall are manipulation, dominance, and her evil nature. Lady Macbeth manipulates Macbeth into believing that he is a coward and a bad husband, which persuades him to agree to the murder of King Duncan. She dwells on the fact that he is a coward, when she says "My hands are of your colour, but I shame/ to wear a heart so white" (2.2.64-65). This instills feelings of embarrassment into his mind, and manipulates him into believing that if he does not murder King Duncan, he will be a weak, cowardly man. Not only is she challenging his manhood, by appearing to be the stronger and braver of the two, but also, by calling his heart "white", she is criticizing his cowardice. The fact that his wife is undermining his masculinity causes Macbeth to want to be stronger, and not to appear weak and timid. When Lady Macbeth yells "Infirm of purpose! Give me the daggers. The sleeping and the dead/ are but as pictures. 'Tis the eye of childhood/ that fears a painted devil" (2.2.53-55), she further contributes to the shame which she has driven into Macbeth's mind. She bluntly tells him that he is acting like a weak, nervous child, and insults him for being afraid of something that is already dead! This shame encourages Macbeth to want to consent to his wife's plan. Another method which Lady Macbeth uses to manipulate her husband's mind is by making him feel guilty for being a bad husband, who breaks his promises: "What beast was't then/ that made you break this enterprise to me?" (1.7.47-48). She knows that by saying this, he will feel remorse for breaking a promise to his wife whom he loves so much. The Power of a Woman :: essays research papers fc The Power of a Woman The familiar saying "Behind every great man is an even greater woman" can certainly hold true in many cases. A woman may very well be the driving force behind any successful man. However, a woman can also use her strong influence in a negative way. This can be seen in Macbeth, where Lady Macbeth is the evil force behind Macbeth's cruelty and evil doings. In Shakespeare's Macbeth, Lady Macbeth is the main reason that Macbeth is transformed from a noble, respected Thane into a ruthless, murderous character. Lady Macbeth fuels his inner desire for power and brings forth his greed and ambition, which both eventually lead to his downfall. The tactics that Lady Macbeth use to drive her husband to this downfall are manipulation, dominance, and her evil nature. Lady Macbeth manipulates Macbeth into believing that he is a coward and a bad husband, which persuades him to agree to the murder of King Duncan. She dwells on the fact that he is a coward, when she says "My hands are of your colour, but I shame/ to wear a heart so white" (2.2.64-65). This instills feelings of embarrassment into his mind, and manipulates him into believing that if he does not murder King Duncan, he will be a weak, cowardly man. Not only is she challenging his manhood, by appearing to be the stronger and braver of the two, but also, by calling his heart "white", she is criticizing his cowardice. The fact that his wife is undermining his masculinity causes Macbeth to want to be stronger, and not to appear weak and timid. When Lady Macbeth yells "Infirm of purpose! Give me the daggers. The sleeping and the dead/ are but as pictures. 'Tis the eye of childhood/ that fears a painted devil" (2.2.53-55), she further contributes to the shame which she has driven into Macbeth's mind. She bluntly tells him that he is acting like a weak, nervous child, and insults him for being afraid of something that is already dead! This shame encourages Macbeth to want to consent to his wife's plan. Another method which Lady Macbeth uses to manipulate her husband's mind is by making him feel guilty for being a bad husband, who breaks his promises: "What beast was't then/ that made you break this enterprise to me?" (1.7.47-48). She knows that by saying this, he will feel remorse for breaking a promise to his wife whom he loves so much.

Tuesday, November 12, 2019

Leonardo Fibonacci Biography

Leonardo Fibonacci was born around 1170 A. D. , and died around 1250 A. D. He was born in Pisa, Italy and died there too. Leonardo’s mom was Alessandra, and she died when he was nine. His father was Guglielmo Bonacci, who directed a trading post Bugia, Barbary. As a young boy, Leonardo traveled there to help him, and that’s where he learned about the Hindu-Arabic numeral system. He recognized that arithmetic with Hindu-Arabic numerals is simpler and more efficient that with Roman numerals and so he traveled throughout the Mediterranean world to study under the leading Arab mathematicians of the time. Leonardo returned from his travels around 1200 and in 1202, age 32, he published Liber Abaci. Through the Liber Abaci he introduced Hindu-Arabic numerals to Europe. Liber Abaci is a book that Leonardo Fibonacci wrote in 1202. In it Fibonacci introduces the so-called modus Indorum (method of the Indians), today known as the Arabic numerals. It shows the practical importance of the new numeral system, using lattice multiplication and Egyptian fractions, by applying it to commercial bookkeeping, conversion of weights and measures, the calculation of interest, money-changing, and other applications. Liber Abaci also posed, and solved, a problem involving the growth of a hypothetical population of rabbits based on idealized assumptions. The solution, generation by generation, was a sequence of numbers later known as the Fibonacci numbers. In the Fibonacci sequence of numbers, each number after the first two, is the sum of the previous two numbers. The sequence is 0, 1, 1, 2, 3, 5, 8, 13, 21, 34, 55, 89, 144, 233, etc. The higher the sequence, the closer two consecutive numbers of the sequence divided by each other will approach the golden ratio ( approximately 1 : 1. 618 or 0. 618 : 1). Leonardo became a guest of the Emperor Frederick II, who enjoyed mathematicians and science. In 1240 the Republic of Pisa honored Leonardo by granting him a salary. In the 19th century, a statue of Fibonacci was constructed and erected in Pisa. Today it is located in the western gallery of the Camposanto, which is a cemetery on the Piazza dei Miracoli.

Sunday, November 10, 2019

Organizational Behavior-No Fair Pay In This Place Essay

The purpose of this paper is to examine the motivational effects of pay level on worker performance. It is discusses some of the elements that contributed to the employees in Western Satellite office to express feelings of inequality. Some of these elements include academic qualifications, educational background, just to mention but a few. The paper also tackles some of the reasons why the New York worker is considered a ‘comparison other’ as opposed to the worker in Seattle. Moreover, the paper explores how the issue of inequality in the case- no fair pay in this place was either resolved or not. For instance, we find in this case that this issue was not resolved. Last but not least, the paper also examines some of the other factors that may have contributed to the dissatisfaction that was experience by the two workers. Some of these factors include; lack of communication, culture, lack of adaptability, lack of empathy, just to mention but a few. Introduction  The purpose of this paper is to examine the case study that revolves around no fair pay in the workplace and the fact that employees working from different cities receive different numerations irrespective of how much responsibility one has within the organization, their academic qualifications and the years of experience within the industry in which they are operating. (Armstrong, 2006, p. 62) Question One What are some of the elements which contributed to the employees feelings of inequality? These include educational background, years of experience, responsibilities that one has and last but not least academic qualifications. The employees were stressed with the kind of work they had to perform such as having heavy load of unhappy clients and their urgent demands, complaining customers, just to mention but a few. (Meredith, 2004, p. 2) Susan was hired based on her degree in Business Administration. She was responsible in planning, problem solving and supervising a number of employees and this included Dan Donaldson, a public relations spokesperson of the company. However, despite all these responsibilities, she received a remuneration of $30,000 per annum. This was very disappointing since she had 20 years of customer relations and supervisory know-how, not to mention the current degree that she had received in business. (Meredith, 2004, p. 3) On the contrary, Helen who was based at the headquarters in New York received $40,000 in only ten months as opposed to 12. This made Susan furious since she had no customer contact, no university education, no one to supervise and no seniority. In a nutshell, Helen had an annual salary of $48,000. (Meredith, 2004, p. 3) Pay determination may possibly have one or more objectives, which may frequently be in conflict with each other. The primary is equity, and this may take numerous forms. They comprise income distribution through reduction of inequalities, defending real earnings (purchasing power), and the notion of equal pay for work of equivalent value. Moreover, pay differentials based on differences in skills are all associated to the idea of fairness. (Deckop, 2006, p. 65) Performance pay systems in organizations are based on assessment of the personality worker, often by their line administrator who may or may not be experienced in process. Performance pay is extensively renowned as contributing to pay inequalities, predominantly in this case (New York and Seattle). (Culbert, 1996, p. 68) Question Two Why the New York worker was considered a ‘comparison other’ but not the worker in Seattle? The New York worker was considered a ‘comparison other’ because the front lines of the job were in Seattle where the client based was centered and the services were rendered. Moreover, employees at Seattle received heavy load of unhappy clients and their urgent demands while she contentedly remained in her comfort zone that was stress free. Research has recommended that some individuals are more flourishing in their careers than others even when they have had equivalent learning and experimental opportunities. One clarification for these disparities may possibly relate to differences between intellectual intelligence (IQ) and emotional intelligence (EQ). IQ measures academic competencies or one’s aptitude to use acquaintance in making decisions and adapting to innovative situations. This can best be illustrated with Helen who works in at the headquarters in New York. However, as much as she is based in New York, all the tasks are carried out in Seattle, and this means that she is not using the little experience and experimental opportunities that she acquired to perform her duties. (Lamal, 1991, p. 72) On the other hand, EQ is a measure of expressive and societal competencies or one’s aptitude to recognize expressive expressions in someone and others. Even though both can be enhanced through training and altered over time, EQ is separate from IQ in that it is one’s aptitude to standardize emotions in reaction to ecological stimulus. EQ has been popularized as an educated skill that is a superior interpreter of life success than intellectual achievement or technological aptitude. This can best be illustrated with Susan and Dan Donaldson who had superior performance, academic achievements, work experience and interpersonal skills. They had to deal with resolving customers issues on a daily basis while Helen and her fellow workers who were based in New York sat and waited for the final produce that came from Seattle. (Harris, 2001, p. 78) The workplace surroundings idea also sees entity firm level performance such as efficiency, productivity, efficiency and competitiveness; as a result of not only the sufficiency supply of human resources with suitable skills, but also a workplace surroundings that incessantly optimizes the use of these skills throughout the way work is intended and prearranged, the suitability, access and association of supports and tools to do the work, the association of decision making, rewards and appreciation for performance. The New York worker is considered a ‘comparison worker’ as opposed to the worker in Seattle since she lacks interpersonal skills, academic achievements, superior performance, just to mention but a few. Despite all these, she is considered the best just because she is based at the head office located in New York. (Bate, 1994, p. 81) On the other hand, the Seattle worker who has all the necessary qualities such as work experience, interpersonal skills and academic qualifications; is looked down upon just because she is operating in Seattle. (Meredith, 2004, p. 2) Question Three  How was the inequality resolved? The inequality was not resolved at all. As a matter of fact, once Mr. James commented that nobody said that it was fair and rather, that was how the staff in New York are remunerated, that was the end of the discussion. Mr. James did not validate his statement, neither did he explain why that was the case. Instead, he was interested in how Susan found out about Helen’s salary. (Meredith, 2004, p. 3) Participation in the labor force is usually regarded as an important measurement of equality. Having a job is significant to individuals. Jobs are a numerically important starting point for livelihoods. They are also significant proportions of social respect, acknowledgment, individuality and self esteem. Even though the sources and solutions for increasing inequality are multifaceted and open to dispute, the corporeal and psychosomatic penalties are real and straightforward. (Mathis, 2006, p. 99) It is understandable that we require more than legislation, bylaw and exacting programs to generate a diverse workforce usual in association. We also need customs of understanding the challenges. This mean examination of ‘what goes wrong’. Both the need for continuous coercive dealings and the phenomena of the turning door or equity tell us regarding the pervasive and systemic character of the status quo in workforce composition and in the organization and conduct of business and government. (Max, 204, p. 104) When individuals talk concerning inequality, they tend to center completely on the proceeds part of the equation. According to the case- no fair pay in this place, there is the gap between the employees in New York and Seattle and this is based on remuneration amongst the employees. (Armstrong, 2006, p. 8) The verification of increasing disparity in the United States and around the globe is both obvious and disturbing. As power, capital, and probability are increasingly concerted in the hands of the extremely few, this age of â€Å"haves† and â€Å"have not† is connected with a wide range of unenthusiastic outcomes for faraway too countless. A good illustration is seen in the case-no fair pay in this place, where Western Satellite Office workers are experiencing inequality problems based on remuneration since they are not based in New York where the head office is situated. They are the ones who experience customer service problems since each and every customer wants to be served and at the end of the day, they feel so stressed and worn out, yet when it comes to remuneration they receive less than what the worker in New York receive. This is not fair since the worker in New York doesn’t experience the pressure that the Seattle worker receives. (Lamal, 1991, p. 106 Question Four What are the other factors which may have contributed to the dissatisfaction experienced by these two workers? Culture A managerial culture affects how the company performs. Culture is the behavior of a group of individuals. This consists of; the beliefs, civilization, acquaintance and practices. Individuals depend on it for security, evenness and the ability to act in response in a given circumstance. (Harris, 2001, p. 92) According to this case, the reason why Helen and Susan received different remuneration was because Helen was situated at the head office in New York. This was the culture of that organization that was based on the location of the city. Therefore, Susan having been situated at Seattle was bound on her $30,000 per annum, and this was regardless of her qualifications. (Meredith, 2004, p. 3) Lack of Communication Generally, lack of communication on the part of the boss contributes to the displeasure among the workers in the association. Communication problems are a purpose of message and organizational procedure, and managerial factors. Effectual communication of performance requirements to all workers will reduce the number of complaints and grievances. Nonattendance of this communication domino effect in workers not performing. For instance in our case, when Susan was about to present her case, Mr. James had already predicted and he simply brushed the matter off by making a comment concerning the issue. He didn’t give room for discussion concerning that matter; neither did he give an explanation nor a satisfactory solution. This resulted to laxity among the workers in the western satellite office. (Bate, 1994, p. 98) By not communicating well enough, Mr.  James avoided to get into dialogue concerning important issues such as, the reason why employees in New York receiving a higher pay as opposed to employees in Seattle. This made him appear unavailable and uncaring to Susan and the employees of Western Satellite Office; this resulted in hurting teamwork spirit and cooperation within the organization. (Deckop, 2006, p. 110) Lack of Self awareness and accurate self-assessment Without self awareness and self-assessment, Mr. James was too quick to brush off the matter that Susan had presented to him. He was unable to accept useful feedback, and he didn’t have a realistic awareness of his strengths or limitations. As a result, it created problems in their work relationships and in their personal relationships. (Culbert, 1996, p. 115) Lack of Empathy When leaders fail to demonstrate sufficient empathy in times of hesitation or crisis, they will probable be seen as unresponsive, hardhearted and in-authentic- all of which will make workers be less supportive and less communicative. The boss may be left feeling misunderstood, and will have complexity â€Å"reading† their workers. This is exactly what Mr. James did and as a result, Susan’s ability to work drastically diminished and she became less concerned with her duties and responsibilities in the workplace. (Mathis, 2006, p. 120) Lack of Adaptability Without elasticity and adaptableness, Mr. James responded negatively to the core issue that was troubling his employee Susan. This revealed emotional strain to Susan since she had to shift priorities; expressed frustration with change; had difficulties adapting Mr.  James responses and tactics to fit the emerging circumstance; and ultimately she was hesitant in taking on new challenges. (Max, 2004, p. 126) Lack of self-management Without good self management, Mr. James reacted precipitately when he predicted that there was bound to be conflict at work. This made him respond to problems in a non-constructive manner that resulted to unwanted consequences such as laxity amongst the employees (Susan). (Harris, 2001, p. 118) Conclusion  In a civilized workplace, individuals who work well ought to be rewarded through decent pay, endorsement and new opportunities, the possibility to build up new skills, admiration from coworker and management, and the individual gratification and satisfaction that comes from doing a job well. Culture determines the type of management, communication, and cluster dynamics within the association. The employees usually recognize this as the excellence of work life which directs their measure of motivation. The concluding outcome is generally performance, human being satisfaction, individual growth and expansion. All these rudiments unite to build the model or structure that the association operates from. However, all these elements are not revealed in our case since Mr. James chose not to allow room for discussion. He lacked communication skills and empathy and as a result, there was poor turnover in Susan’s output. Generally, in an organization, employers should be open with their employees and allow a forum for discussion and participation. For instance in this case, Mr.  James would have allowed Susan to present her queries and later on try to explain to her why the workers in New York had to receive a better pay than workers in Seattle. Moreover, there should be restructuring of some of the rules in Western Satellite Office and promote job enrichment. This will facilitate enlargement of the individuals within the association, better worker performance for the association, there will be maximum use of human resources for the general public at large (both in New York and Seattle), enlargement of the individual, and self-actualization of the individual.

Friday, November 8, 2019

The Ab Factor

The Ab Factor Free Online Research Papers This article may be one of the most informative passages to what many may refer to as the fitness â€Å"bible†. It is the clearest, most concise version I have ever seen. For many followers and non believers, this may very well be a sure trip to the six pack promise land. Being that I am a part-time health concise individual (notice I said part-time), I have tried to explain to people that no matter how hard you work those stomach muscles, they won’t see the light of day until you loose the excess body fat. Theoretically speaking the mid section is and always will be the first body fat on last body fat off. The first subject this article brings to light is genetics. Genetics may not be the GCF (Greatest Common Factor) of hidden abs, but it is definitely a major one so let’s do the math. The shape of the abdominals is decided at birth and can not be changed by merely exercise alone. One must maintain a healthy diet in addition to exercise to help maintain the balance of this equation. Another factor the article takes into consideration is body fat. This is considered the most important but often ignored factor of them all. The percent of body fat must be lowered in order for your abs to show up. This could be anywhere from eleven to a super lean look of six percent. Simple mathematics but a not so simple process. Speaking of a not so simple process comes the nutrition factor. The article speaks about â€Å"eating clean† and eliminating bad foods from your diet. Can’t get a â€Å"six pack† eating a chocolate bar or a cheese burger. A good nutrition plan starts in the kitchen and in my opinion, should stay there. Keeping yourself fully hydrated is also essential by dinking plenty of water. This is definitely a plus because it aids in maintaining a healthy diet by satisfying food cravings. After all the genetics, the body fat, and the nutrition comes the most dreaded of them all, exercise. The article states that primary training is the biggest mistake people make when going for the wash board look. The main focus needs to be on resistance training that includes the entire body and not just the mid section alone. This can be achieved by using compound lifts, body weights and sprint training to focus on what they call the bodies metabolic hot spots. These areas include the back, lower body and chest. Cardio would be a good kick start for the metabolism as well as a full body work out. In summary, the best way to achieve the ultimate set of abs is not to focus on that area alone but the entire body. If you are trying to burn fat and build muscle at the same time, you need to understand what makes you gain and lose weight (or stay them same). Everyone has a Basic Metabolic Rate (BMR), which is the basic rate at which you burn calories. If you eat more calories than your BMR on a daily basis, you will gain weight. If you eat less, you lose weight and if you eat right at your BMR, you stay the same. Taking this into consideration, its not about the 500 crunches, its about the 500 extra calories. Cutting back on certain food, exercising regularly and being consistent is the only way you can get to the square root of the problem, the ab factor! Research Papers on The Ab FactorMarketing of Lifeboy Soap A Unilever ProductNever Been Kicked Out of a Place This NiceThe Spring and AutumnIncorporating Risk and Uncertainty Factor in CapitalArguments for Physician-Assisted Suicide (PAS)Genetic EngineeringEffects of Television Violence on ChildrenMind TravelPersonal Experience with Teen PregnancyInfluences of Socio-Economic Status of Married Males

Tuesday, November 5, 2019

Exploding Mentos Drink

Exploding Mentos Drink A friend sent me a link to a Wired how-to project called The Manhattan Project in which you freeze a Mentos candy into an ice cube and place it in a carbonated drink. When the ice cube melts, the wax surrounding the candy will be exposed and the drink should erupt. Does it work? Lets find out. Exploding Mentos Drink Ingredients The drink in the original recipe called for whiskey, sweet vermouth, and bitters (basically a Manhattan plus diet cola), but you can make a rum and coke or whatever you like or just try the non-alcoholic version using two ingredients: diet colaa Mentosâ„ ¢ candy Make the Exploding Drink Ill tell you right up front: a drink with soda and Mentos wont explode unless it is in an enclosed container. Exploding drinks make messes, plus they tend to spray out shards of glass, so its a good thing this drink isnt so violent. Erupting is more what youre looking for here. If you want to cause an unexpected eruption, freeze a single Mentos candy into the well of an ice cube tray. Youll get the best results if you wait until the ice is almost frozen and then add a Mentos candy to each cube so that its near the surface of the ice. You dont want to soak the candy in cold water or its coating will dissolve. If that happens, all youll get when you mix it with diet cola is candy-flavored cola. The premise is that the Mentos will become exposed as the ice cube melts. When the wax coating of the candy reacts with the diet soda, the drink will fizz and bubble like the classic Mentos and diet soda fountain. If youre doing the project on-purpose or else dont mind getting caught dropping a Mentos into someones carbonated drink, you can simply plop the candy in the soda no ice cube needed. How the Mentos in Ice Cubes Trick Works Among other things, the gum arabic that coats a Mentos candy lowers the surface tension of the soda, allowing carbon dioxide bubbles to rise and expand more easily. The candy coating traps the gas, forming bubbles and foam. When I tried this project, I didnt get a spectacular eruption, but you can expect somewhat better results if you use a narrow glass for your drink. Except that the Mentos flavors the drink, I dont think someone with a Mentos-laced ice cube would notice much happening or suffer from an out-of-control foaming drink. The project is still pretty fun.

Sunday, November 3, 2019

Implementing Change Assignment Example | Topics and Well Written Essays - 3500 words

Implementing Change - Assignment Example In 1999 with major changes taking place at the national level of government in the form of devolution, local councils were scrambling to 'keep their heads above water'. During this time period, it was evident that each department was focused crisis after crisis within their own department and there was no vision for propelling the city into a cohesively run organisation (Leeds City, 2006, screen 1). Seeing the need for organisational change the leadership of Leeds City Council set about creating a culture of unified strategic direction and bring together all employees to focus on meeting the strategic needs of the city. In order to achieve this, the Chief Executive and his staff focused on development of the Council's Core Values as a first step in the process of organisational change. Once the core values had been identified council's next step was to begin to create the atmosphere conducive to change. In the following paragraphs we will examine how Leeds City Council was able to successful launch a sweeping organisational change and a shift to continuous process improvement. Upon arriving at the council core values the Chief Executive understood that without the support of employees the core values established would be nothing more that words on paper. The next step the executive undertook was to educate and gain acceptance for this move towards organisational change. ... l the "Vision for Leeds" into the culture of the council and ensure management understood 'the council's objectives and the cultural change needed to bring them about' (Leeds City, 2006, screen 1). The Road to Change Before an organisation can effectively make a change they have to understand what change is and what it is not. "The creation of healthy change is about living comfortably with conditions of constant change, and finding ways to create, within those conditions, pathways for accomplishing desired objectives through continuous adaptation." (Discussion, 2005) Understanding and redefining the complexity of this requires a three-fold approach. First, change does not mean we throw away the old, rather we build upon where we are; secondly, change is not finite, we can not view change as something we are finally doing or somewhere we will be - Change is constant; and thirdly, with change there is no return to normalcy. The continual process of evolving, of change, if you will, becomes the constant with the organisation. How we once did things as an organisation is in the past. Kotter and Cohen point out the biggest hurdle an organisation faces when initiating change is not dealing with proces ses or systems, but rather, changing the behaviour of the members of the organisation itself. Once that is accomplished the rest falls neatly into place. (2002) This requires a new way of thinking within the organization, a shifting from old preconceived ideas and notions and a movement towards envisioning and creating the means for this change to occur. The organization transforms itself based on the shifting thought processes brought on by the change. An organization is not the outward faade of the building and internally the hierarchy of management. An

Friday, November 1, 2019

Mitosis Essay Example | Topics and Well Written Essays - 1000 words

Mitosis - Essay Example Cell division is a basic phenomenon of life in living organisms. It is known that the process of cell division, irrespective of the animal species, remains invariably the same. It is here that we comprehend that despite being the different in their outward appearance this basic phenomenon invariably remains the same. In byline, the author of the article, Daniel Needleman, has said that experimentation has been able to understand the difference that exists in this cell division phenomenon among the animals. This difference is found out to reside on the chromosomal and molecular level rather on higher level view. This difference can also exist even between similar organisms. Over a long period of time, it was known that spindle fibers that segregate chromosomes during cell division show great variation in size and shape, but the underlying reason was not discovered. Experiments have shown that the embryos that undergo the process of division, after repeated division cycles, considerabl y reduced in size and so did the spindle sizes. The experiments conducted on organisms like mouse have revealed many facts yet it has been difficult to ascertain any explicit cause to the phenomenon. Thus, another aspect that is attributed with the change is the change in biochemistry during the course of cell division. To infer a proximal result of the obvious phenomenon, a causative analysis is used as help. Cellular biology research has, therefore, evaluated a relationship during the course of development, between protein and phenotype. ... This experiment is multistage causal analysis procedure (Wilbur and Held). Embryos are subjected to tests during different stages of their development. It revealed that the change in size of spindles was not caused by division rather it was related to the state of cytoplasm. This in turn puts a question mark on how cytoplasm produces such change. To answer this question a categorization of the same microtubules was made. Early stages revealed less de-polymerization or catastrophe to these microtubules, as compared to those in the late stages. This revelation through stag-wise analysis did not reveal the true picture that could be able to answer above mentioned questions. Varying lengths of microtubules during the de-polymerization cannot be understandable reason. Later Wilbur and Heald used another approach to understand the size variation of spindles. Cytoplasm and its effects on elementary protein structures of spindles were analyzed. Proteins responsible for microtubule catastroph ies in different extracts were identified as Kinesin-13 and Kif2a. Kif2a was thought to be the reason of change in spindle sizes but extracts have revealed that concentration of this type of proteins remains constant during all stages of development. A co-existing phenomenon of importin-alpha attaching to the membrane or leaving the cytoplasmic area caused kif2a to be more active, that in turns increases microtubule catastrophy rates. (Wilbur Heald, 2013) Suggestion about this mechanism is perhaps understandable with the help of biochemistry, as with change in size due to successive divisions cause greater surface to volume ration than in larger cells. The only point in this understandable phenomenon is that why importin-alpha tends to be sequestered with the cell membrane